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몽발개발
Randomized Clinical Trial of Real-Time fMRI AmygdalaNeurofeedbackfor Major Depressive Disorder: EffectsonSymptoms and Autobiographical Memory Recall 본문
뇌공학/논문 정리
Randomized Clinical Trial of Real-Time fMRI AmygdalaNeurofeedbackfor Major Depressive Disorder: EffectsonSymptoms and Autobiographical Memory Recall
집사 몽이 2020. 7. 20. 16:52반응형
읽은 날 | 2020.07.20. | 학술지 | Medical knowledge |
제목 | Randomized Clinical Trial of Real-Time fMRI Amygdala Neurofeedbackfor Major Depressive Disorder: Effectson Symptoms and Autobiographical Memory Recall |
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저자 | Kymberly D. Young, Ph.D., Greg J. Siegle, Ph.D., Vadim Zotev, Ph.D., Raquel Phillips, B.S., Masaya Misaki, Ph.D., Han Yuan, Ph.D., Wayne C. Drevets, M.D., Jerzy Bodurka, Ph.D. |
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한줄요약 | rtfMRI amygdala neurofeedback로 positive memory에 대한 HRF를 증가시키는 방법은 major depressive disorder 개선에 효과가 있다. | ||
초록 | Depression is a common and disabling condition (1). With approximately two-thirds of patients not responding fully to treatment (2), investigation into novel therapeutic approaches is warranted. One novel approach is real-time functional MRI neurofeedback (rtfMRI-nf ), in which an individual receives information about the blood-oxygen-level-dependent (BOLD) signal from their brain in real time and learns to selfmodulate this signal (3, 4). Emerging evidence suggests that rtfMRI-nf has clinical utility in chronic pain (5), smoking cessation (6), anxiety (7), and depression (8, 9). In the present study, we conducted a randomized clinical trial to test the therapeutic potential of rtfMRI-nf training to enhance the amygdala hemodynamic response to positive autobiographical memory recall for depression. | ||
키워드 | amygdala neurofeedback, MDD(Major depressive disorder) | ||
의의 | 우울증 증상을 neurofeedback으로 완화시킬 수 있다는 실험적인 증명. 항우울제 처방이나 cognitive-behavioral therapy을 사용한 효과와 비교해도 유의미한 수준. |
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비판점 | Positive memory에 대한 정량적 측정(가능하다면) 필요. HRF 측정을 통해 어느정도의 positive한 memory가 얼마나 영향을 미치는지 측정할 수 있을 것 같다. |
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